Ntụ ntụ Rotundine dị ọcha (l-tetrahydropalmatine, l-THP)

Rotundine, nke a makwaara dịka l-tetrahydropalmatine (l-THP), bụ ihe mejupụtara ọgwụ nwere ihe ndị na-emetụta sistemụ akwara etiti na sistemụ obi. Akọpụtala na ọ nwere mmetụta mgbu, ọgwụ mgbu, hypnotic, na anxiolytic. Na mgbakwunye, egosila na ọ nwere mmetụta nchebe na mmerụ ahụ ischemia-reperfusion nke ụbụrụ na myocardial. A makwaara Rotundine maka ikike ya ịgbanwe iguzogide ọtụtụ ọgwụ na mkpụrụ ndụ kansa na ihe ndị na-egbochi ọwa calcium.
A pụrụ inweta ya site na mkpụrụ osisi Stephania tetrandra na Corydalis yanhusuo, ma ọ bụ site na usoro mmepụta kemịkalụ. A na-emepụta ya site na tetrahydropalmatine site na mbelata, nkewa, na mmeghachi omume alkalization. A pụrụ imepụta tetrahydropalmatine nke a na-enye iodine site na tetrahydropalmatine site na alkalization na oxidation maka njikọta ugboro ugboro.
Maka ọgwụ ọgwụ, a na-amịkọrọ Rotundine nke ọma mgbe a ṅụchara ya n'ọnụ, a na-ekesakwa ya n'ime anụ ahụ adipose, wee soro ya n'akpa ume, imeju, na akụrụ. A na-esikarị n'akwara apụta ya. Ọmụmụ ihe emere na oke bekee na oke bekee egosila na Rotundine nwere ike ịbanye n'ime ihe mgbochi ọbara-ụbụrụ wee banye n'ime anụ ahụ ụbụrụ, ebe ụbụrụ nwere ike ịda ala karịa mkpokọta ọbara mgbe awa abụọ gachara.
Maka mmetụta ọjọọ, Rotundine nwere ike ibute ụra, isi ọwụwa, ike ọgwụgwụ, ọgbụgbọ, na mgbe ụfọdụ ihe mgbu nfụkasị ahụ. Ihe ndị a na-akpachara anya gụnyere izere ojiji n'ahụ ụmụ nwanyị dị ime na ndị na-enye nwa ara, ịmara na enwere ike ịnagide ojiji ogologo oge, na ịkpachara anya mgbe a na-enye ọgwụ ndị na-ebelata nrụgide n'ahụ etiti, yana mgbanwe dose kwesịrị ekwesị ma ọ bụrụ na ọ dị mkpa.
Na nchịkọta, Rotundine bụ ngwakọta nwere mmetụta dị iche iche nke ọgwụ, ihe ndị o ji eme ya na-eme ka ọ bụrụ isiokwu nke nnyocha dị iche iche, gụnyere njikwa ihe mgbu, ahụike obi, na ọgwụgwọ kansa. Maka ozi ndị ọzọ kpọtụrụ anyị.grace@biowaycn.com.