Sinomenine Hydrochloride ntụ ntụ

Mgbochi mgbochi: na-ebelata mbufụt.
Analgesic: Na-enye ihe mgbu.
Immunosuppressive: na-egbochi ọrụ sistemu ahụ ji alụso ọrịa ọgụ.
Anti-rheumatic: Na-agwọ ọrịa ogbu na nkwonkwo.
Neuroprotective: Na-echebe mkpụrụ ndụ akwara pụọ na mmebi.
Anti-fibrotic: Na-egbochi ma ọ bụ na-ebelata fibrosis anụ ahụ.

Zitere anyị email

Nkọwa ngwaahịa

Mkpado ngwaahịa

Okwu Mmalite ngwaahịa

Sinomenium Hydrochloride bụ ngwakọta kemịkalụ sitere na osisi Sinomenium acutum, nke a na-ahụkarị na East Asia. Ọ bụ alkaloid nke ejirila na nkà mmụta ọgwụ ndị China maka mgbochi mkpali na analgesic Njirimara. Ụdị hydrochloride bụ nnu nke na-eme ka ogige ahụ dịkwuo mma na nkwụsi ike, na-eme ka ọ dịkwuo mma maka iji ọgwụ eme ihe.
A mụọla Sinomenine Hydrochloride maka mmetụta ọgwụgwọ ya nwere ike ịgwọ ọnọdụ ndị dị ka ọrịa ogbu na nkwonkwo, n'ihi ikike o nwere imezi usoro ahụ ji alụso ọrịa ọgụ ma belata mbufụt. Ọ na-arụ ọrụ site na igbochi mmepụta nke cytokines pro-inflammatory na ndị mgbasa ozi ndị ọzọ na-etinye aka na nzaghachi mkpali.
Na mgbakwunye na mmetụta mgbochi mkpali na analgesic, Sinomenine Hydrochloride egosiwokwa ike na neuroprotection, mgbochi fibrosis, na mgbochi tumor ọrụ dị iche iche preclinical ọmụmụ.

Nkọwapụta

Aha aha: (9a,13a,14a) -7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-otu, monohydrochloride
Nọmba CAS: 6080-33-7
Ndị otu: Cucoline NSC 76021
Ụdị ihe omimi: C19H23NO4 • HCl
Arọ Formula: 365.9
Ịdị ọcha:≥98% kristal siri ike
Solubility(Mụta maka ọdịiche dị na Solubility)
DMF: 30 mg / ml
DMSO: 30 mg / ml
Ethanol: 5 mg / ml
PBS (pH 7.2): 5 mg / ml
Mmalite: Osisi/Sinomenium acutum
Ozi Mbupu & Nchekwa:
Nchekwa -20 Celsius
Mbupu: Okpomọkụ ụlọ
Nkwụsi ike:≥ 4 afọ

Ihe	Nkọwapụta	Nsonaazụ
Nyocha (HPLC)	98.0%	98.12%
Ọdịdị	ọcha ntụ ntụ	Na-akwado
Nha urughuru	98% site na 80 mesh	Na-akwado
Isi	Njirimara	Na-akwado
Detụ ire	Njirimara	Na-akwado
Njirimara anụ ahụ
Ọnwụ na ihicha	≤0.5%	0.38%
Ash	≤0.5%	0.46%
Ọla dị arọ
Ọla dị arọ (dị ka Pb)	Ụkpụrụ USP (<10ppm)	<10ppm
Arsenic (As)	≤2pm	0.78pm
Ndu (Pb)	≤2pm	1.13pm
Cadmium (Cd)	≤lppm	0.36pm
Mercary (Hg)	≤0.1pm	0.01pm
Ihe fọdụrụ na pesticide	Achọpụtaghị ya	Achọpụtaghị ya
Ọnụ ọgụgụ Plate	NMT 10000cfu/g	680 cfu/g
Mkpokọta yist & ebu	NMT 100cfu/g	87 cf/g
E.Coli	NMT 30cfu/g	10 cfu/g
Salmonella	Ihe ọjọọ	Ihe ọjọọ
Mmechi	Dabara n'ụkpụrụ ụlọ ọrụ

Atụmatụ

Isi mmetụta Sinomenine Hydrochloride gụnyere:
(1) mgbochi mkpali: na-ebelata mbufụt.
(2) Analgesic: Na-enye ihe mgbu.
(3) Immunosuppressive: Na-egbochi ọrụ sistemu ahụ ji alụso ọrịa ọgụ.
(4) Anti-rheumatic: Na-agwọ ọrịa ogbu na nkwonkwo.
(5) Neuroprotective: Na-echebe mkpụrụ ndụ akwara pụọ na mmebi.
(6) Anti-fibrotic: Na-egbochi ma ọ bụ na-ebelata fibrosis anụ ahụ.

Ngwa

A na-ejikarị Sinomenine Hydrochloride mee ihe na mpaghara ndị a:
(1) Rheumatology: Ọgwụgwọ ọrịa ogbu na nkwonkwo.
(2) Nlekọta mgbu: Mbelata nke mgbu na-adịghị ala ala.
(3) Mgbochi mgbochi: Mbelata mbufụt.
(4) Immunomodulation: Mgbanwe nke usoro ahụ ji alụso ọrịa ọgụ.
(5) Neuroprotection: Enwere ike iji ya mee ihe na ọgwụgwọ neuroprotective.

Nkọwa mmepụta

Enwere ike ichikota usoro mmepụta nke Sinomenine Hydrochloride Powder dị ka ndị a:

Nkwadebe ogwu:Na-ehicha na ihicha ihe ọkụkụ.
Mwepụta:Iji ihe mgbaze dị ka ethanol wepụ sinomenine na ihe ọkụkụ.
itinye uche:Na-ekpochapụ ihe mgbaze iji tinye uche na ọdịnaya sinomenine.
Alkalization:Ịgbanwe pH iji gbanwee sinomenine na ụdị nnu ya.
Mwepụta Liquid-Liquid:Na-asachapụ ihe mgbaze organic dị ka anisole ma ọ bụ 1-heptanol.
ịsa:Ịsacha mmiri mmiri iji wepụ adịghị ọcha na ihe mgbaze.
Acidification:Na-ebelata pH iji kpalite sinomenine hydrochloride.
Crystallization:Na-akpụ kristal nke sinomenine hydrochloride.
NkewaCentrifuging ma ọ bụ nzacha iji kewaa kristal na ngwọta.
ihicha:Iwepu mmiri fọdụrụnụ na kristal.
igwe igwe:Na-egweri kristal a mịrị amị n'ime ntụ ntụ dị mma.
Ịsafe:Na-eme ka nkesa nha nha anya otu.
Njikwa ogo:Nnwale maka ịdị ọcha, itinye uche na ụkpụrụ microbiological.
Nkwakọ ngwaahịa:Nkwakọ ngwaahịa adịghị mma na nchekwa maka nkesa.

Nkwakọ ngwaahịa na Ọrụ

Nchekwa: Debe ebe dị jụụ, kpọrọ nkụ na ebe dị ọcha, Chebe mmiri na ọkụ ozugbo.
Nnukwu ngwugwu: 25kg / drum.
Oge ndu: 7 ụbọchị mgbe iwu gị gasịrị.
Ndụ shelf: afọ 2.
Nkwupụta: Enwere ike nweta nkọwapụta ahaziri iche.