Akụkọ - ihe a na-ahụkarị akwụkwọ na-egbu egbu!

I. Okwu Mmalite

Ndubata

Kedu uru ahụike nke Ginkgo biloba wepụ ntụ ntụ (2)

Ginkgo akwukwobụ ihe dị oke ọnụ ahịa na-arụ ọrụ site na akwụkwọ ginkgo. Ihe ndị bụ isi bụ flavonoids na ginkgo. Ọ bụ ihe na-arụ ọrụ pịrị apị (Platelet na-arụ ọrụ, ihe na-arụ ọrụ) onye na-anabata ya. Ihe omume ọgwụ ya gụnyere: Mmelite ụbụrụ n'ụba na metabolism; ịbawanye ọrụ nke cell super super supertotase dismutase (sod) na gsh-px), na ibelata membrane mikpuru membrane mikpuru memxided lipids (MDA). Mmepụta, scaven ọnọ radierals, na-egbochi mmebi nke Cardiomyocytes na sel na-ahụkarị; Ọrịa na-emegidekọta platelalet plateg, na-agbanyekwa nsogbu na lipid metabolism kpatara na platelet paaf; Meziwanye konalry na-ekesa obi ma chebe byocardium na-echebe; Mụbaa nrụrụ mkpụrụ ndụ ọbara ọbara, belata ọbara ọbara, ma kpochapụ ọrịa ụfọdụ. Kpoo njikọta nke Centomboxan (Txa2) ma na-akpali mwepụta prostaglancin pgi2 site na sel endothelarial.

Isi Iyi

Ginkgo biloba bu akwukwo nke Ginkgo biloba L., osisi nke Ginkingo. Ọpụpụ ya (EGB) nwere ọrụ dịgasị mma maka ahụike dịgasị iche ma na-ejikwa nri na ịchọ mma. Ngwakọta kemịkal nke ginkgo dị oke mgbagwoju anya, ihe karịrị 140 ogige nke dịpụrụ iche na ya. Flavonoids na terpene na terpene bụ ihe abụọ na-arụ ọrụ nke ginkgo. Na mgbakwunye, ọ nwekwara nke polyprenol, acids organic, polysaccharides, amino acids, phenols, na ihe ndị na-achọ ihe. Dabere na ọnụ ọgụgụ na-ezughị ezu, akwụkwọ mbadamba Ginkgo dị ugbu a bụ EGB761 mepụtara dịka usoro Schwabe si dị. Ọ na-apụta dị ka agba aja aja-odo na-enwe obere akwukwo ginkgo. Ihe mejupụtara kemịkalụ bụ 24% flavonoids, na-erughị larịị 6%, ihe na-erughị 0.0% Caanthocylic ,.0% Catechiid Gylyconoid, na ogige polymer. %, inorganic okwu 5.0%, mmiri gajeter 3.0%, ndị ọzọ 3.0%.

Njiri mara na usoro

Mkpụrụ osisi Ginkgo nwere ike iwepu radicals free radicals, lipid peroxidation free radicals free radicals, wdg. N'otu oge ahụ, ọ nwekwara ike ịhazi ma melite ọrụ enzymes antioxidant dị ka supertoide dismutase na glutathe peroxidase. Ahụhụ antioxidant nke flavonoids na EGB karịrị nke vitamin, ọ nwere mgbochi Mwakpo radical na vitro.

Mmetụta antioxidant nke Ginkgo wepụtara site na ụzọ dị iche iche dị iche iche dị iche, yana mmetụta antioxidant nke nsị nchara na ngwaahịa ndị a nụchara anụcha dịkwa iche. Ma Xihan et al. Achọpụtara na mmanụ ather-ethanol nwere mmetụta kachasị sie ike na rapaesaed mmanụ atụnyere na usoro nkwadebe dị iche iche. Ikike antioxidant nke crude ginkgo na-adịtụ elu karịa nke wepụ akọtara. Nke a nwere ike ịbụ ihe na - ewepu ihe ndị ọzọ na - egbochi ọgwụ ndị ọzọ, dị ka ihe nkiri ndị ọzọ, amino acid, tanniids, alkaloids, na ihe ndị ọzọ na - enwe ihe ndị ọzọ na - akpata.

Usoro Nkwadebe Nkwadebe

(1) tozọ ndị na - emegharị ihe dị iche iche n'oge a, usoro a na - ejikarị n'ụlọ na mba ọzọ bụ usoro ndọpụta nke organic. Ebe ọ bụ na ọ bụ ihe na-enye ihe na-egbu egbu bụ ihe na-egbu egbu ma ọ bụ na-agbanwe agbanwe, a na-eji Ethanol dị ka mmịpụta. Nnwale nke Zhang Yonghong na ndị ọzọ gosipụtara na ebe kachasị mma maka iwepụ flavonoids site na mmịpụta ahụ bụ ugboro 10, ọnụ ọgụgụ nke mmịpụta bụ ugboro atọ, na oge ọ bụla na-atụgharị uche maka 1.5 awa.

(2) ụzọ etịpụ enzyme wang hrui et al. Nnwale nke ngụkọta nke ahịhịa na-abawanye ma wepụta mkpụrụ osisi ma wepụta ya, mkpụrụ ahụ nwere ike iru 2.01%.

(3) Mpempe akwụkwọ ultrasonic mgbe ọgwụgwọ ultrasonic nke ginkgo, akpụkpọ ahụ na-agbaji, na mmegharị nke ahịhịa na-eme ngwa ngwa, nke na-akwalite mgbasa nke ihe ndị na-arụ ọrụ. Ya mere, ultrasonic mmịpụta nke flavonoids nwere uru dị ukwuu. Nsonaazụ nnwale ahụ nwetara site na Liu Jingzhi et al. Gosi na ọnọdụ usoro nke mmịpụta ultrasonic bụ: ugboro abụọ 40kHz, oge ultrasonic oge 55min, okpomọkụ 35 Celsius C, ma guzoro maka 3h. N'oge a, ọnụego mmịpụta bụ 81.9%.

Akwukwo icho oru

Flavonoids na akwụkwọ ginkgo nwere ihe mgbochi antioxidant ma enwere ike ịgbakwunye mmanụ na achịcha dị ka antioxidants. Ngụkọta flavonoids na-acha odo odo na-acha odo odo ma nwee slubality sọlị, ma na-agbanye mmiri na ụbụrụ, yabụ mkpokọta flavonoids nwere ike iji ya. Mmetụta. A na-ahazi Ginkgo biloba n'ime ultrafine ntụ ma gbakwunye na nri. A na-etinye akwụkwọ finkgo ma tinye ya na achịcha, bisikiiti, swiiti, na 10% iji hazie nri na-ahụ maka nlekọta ahụike.
A na-eji akwụkwọ Ginkgo dị ka ihe mgbakwunye nri na Canada ma bụrụ onye a kwadoro dị ka ọgwụ ndị ahụ na Germany na France. A na-etinye akwụkwọ Ginkgo na United States Poccopoeia (mbipụta 24) ma enwere ike iji ya mee ihe dị ka mgbakwunye nri na United States.

Nsonaazụ ọgwụ

1. Mmetụta na sistemụ obi
(1) Ginkgo akwukwo nwere ike igbochi ọrụ AnZyme (Ace) (ACE)
(2) Ginkgo akwukwo nwere ike igbochi mbepu nke umu nwoke bu oria ogwu nke mmadu na ndi mmadu na - eme ka ihe ojoo di egwu. Ọ nwere ike imikpu ọdụ ụgbọ mmiri Cardiac nke sitere na Cardiac allergies na geinea ezì.
(3) Ginkgo Akwụkwọ nwere ike ịgbasawanye akwara nke nwamba na nkịta, na-abawanye ọbara ụbụrụ, ma belata nguzogide vaskụlal. Mpempe akwụkwọ Ginkgo nwere ike igbochi mmụba na dayameta minesentic na dayameta mesentier kpatara site na mkpọgide incotoxin. Na Canine Endotoxin, Ginkgo biloba na-egbochi ọrịa mgbochi na-agbanwe; Na atụrụ ngụgụ, Ginkgo biloba wepụ na-egbochi horpermory Edema kpatara ọrịa na-enweghị ike nke lympphatic na-akpata nke endotoxin kpatara.
(4) Okegbọ ahụ bụ ingratitoneal injected na 5ml / n'arọ nke ginngo akwukwo flavonoids kwa ubochi. Ka ụbọchị iri anọ gachara, ihe owuwu ọnya ahụ belata nke ukwuu. A na-ahụkwa ndị websingo biloba (20 mg / kg kwa ụbọchị) na-ejikwa oke bekee na-enweta nri nkịtị na hyperchololestemilemic. Mgbe otu ọnwa gasịrị, ọkwa nke cholesterol na-akụ nke cholesterol na plasma na aorta nke oke bekee na-anagide nri atheredonic na-ebelata nri. Agbanyeghị ọkwa cholesterol efu na-agbanwe agbanwe.
(5) Ginkgo Terpene bụ ihe mgbochi pọpụ akọwapụtara nke ọma. Ginkgo akwukwo ma obu ginkgo terpene nwere ike igbochi platelet-na-arụ ọrụ (paf) na cycloOxygenise ma ọ bụ lipoxygenise. A na-ewepụta akwụkwọ Ginkgo nke ọma na ngwakọta plateozed nke paf ma ọ bụghị metụtara nchịkọta ADP.

2. Mmetụta na sistemụ akwara
(1) Ginkgo akwukwo na-emetụta usoro endocrine na mmekọrịta dị n'etiti usoro ahụ ji alụso ọrịa ọgụ na sistemụ akwara na etiti site na igbochi ọrụ paf. Ọ nwere ike ịkwalite Metabolism ụbụrụ ma melite ọrụ ebe nchekwa.
(2) ginkgo terpones nwere mmetụta antidepressant, nsonaazụ antiasis na etiti mononoatergic ụjọ na Centhoasis monosgic.
(3) Na mgbakwunye na eziokwu ahụ na-eme akwụkwọ nri Ginkgo nwere ike ime ka nsogbu dị iche iche na-eme ka ọ bụrụ nano2 nke Nano2 nwere ike metụtara mmụba ọbara na-abawanye metabolism n'ọbara n'oge hypoxia.
(4) Ginkgo akwukwo nke ukwuu na-eme ka nsogbu uche nke gerbils nke na-eme site na akwara akwara nke Ischemi na nnọchi anya; Kwado ọrụ nkịta mgbe ọtụtụ ụdọ na-ahụ maka ụma na -eweghachite na mgbake neuronal na mbelata nke neuronal na-esochi ya na hippocamps ụbụrụ; Na-ebelata oke nke ATP, AMP, Creatine phosphate na ụbụrụ bụ ụma nke nkịta Mongrel. Ginkgo biloba Lacketne b bara uru na ọgwụgwọ ọgwụgwụ nke ọrịa strok.

3. Mmetụta na usoro nri
(1) Ginkgo akwukwo nwere ike ime ka ọnya afọ na eriri afọ nke paf na-ebu, ma nwee ike imebi ihe mgbochi ga-egbochi Ethanol.
(2) na ụmụ oke na imeju na-eme ka ọ bụrụ na bile na-eme ka ọ bụrụ nke a na-agbanwe agbanwe nke ukwuu na-ebelata ike nrụgide na-enweghị atụ, ma na-eme ka ndị na-efe efe na-eme ka ọ bụrụ nke a na-ahụ maka ya. Nke a na-egosi na websaịtị Ginkgo nwere mmetụta a na-agwọ ọrịa na imeju. Ọ nwere ike igbochi usoro nke oxyxy oxyxiss na òké nnukwu ọrịa choleststokinin kpatara. Ginkgo Tarpene Lactone B nwere ike inwe ọrụ na ọgwụgwọ nke nnukwu pancreatitis.

4. Mmetụta na usoro iku ume
(1) Ethanol Mwepu nke Ginkgo Biliba nwere mmetụta zuru oke na tracheal na-eme ka ọ bụrụ nke na-eme ihe nkiri nke Guinea nke Guine.
(2) injection nke mpempe akwụkwọ ginkgo nwere ike igbochi ọgwụ ndị na-eme ihe na-eme ka paf na ovalbimin site na paf na ovalbimin nke Antigens na-akpata, mana ọ naghị emetụta hypersressponess nke Indometacin kpatara.
(3) inhalation nke aerososized na-egbochi akwụkwọ nri na-egbochi bronchoconconconcontaisations mana ọ na-egbochi mbelata nke mkpụrụ ndụ na-acha ọcha na oosinophils nke paf. Wepụta akwụkwọ Ginkgo dị ezigbo mkpa na-egbochi ọnya na-emeso hyperssponess.

5.
GinkgobifLononononononononononononononononoids, ginkin biloba, na Qucertin na ginkgo na - eme ka ihe nile na - egbochi ihe niile, ọkachasị ebe ọ bụ na Qucertin nwere ọrụ siri ike. A na-eme nnwale na oke oke ma achọpụtara na mmiri ginng / ml) nwere ike iwelata mmetụta nke ọbara na-eme ka ọrụ ọbara ghara ime ka ọrụ ọpụpụ.

7. Ọrụ na ọjụjụ transplant na mmeghachi omume ndị ọzọ
Oge mmịpụta akwụkwọ Ginkgo nwere ike ime ka oge dị larịị nke anụ ahụ, obi hetenotopic xitograpps. Mkpụrụ osisi Ginkgo nwere ike igbochi mmega ahụ sitere n'okike KC526, ma nwee ike igbochi ọrụ na-egbu mmụọ sitere na ibe ya na-akpata.

8. Anti-akpụ mmetụta
Mkpụrụ osisi na-acha akwụkwọ ndụ akwụkwọ ndụ akwụkwọ ndụ nke gingoba biloba, abụba na-egbu egbu, nwere ike igbochi nje Epstein-Bar. Heptadentene Salylic acid na bilo-betin nwere ọrụ inbibitory; Ngụkọta flavonoids nke ginkgo nwere ike iwelie Thymus ibu nke ụmụ oke. Na ọkwa ọrụ sod, na-ekechi ike nke ahụ ike nke nwere ike imegide ike. Qucertin na Myricetin nwere ike igbochi ihe omume nke Carcinogens.

Ndetu na contraindications

Mmeghachi omume nke Ginkgo: oge ụfọdụ ga-emeju afọ ojuju, dị ka Anorexia, ọgbụgbọ, nsị, na-emebi, wdg.; Enwekwara ike ịbawanye obi obi, ike ọgwụgwụ, wdg, mana ndị a anaghị emetụta ọgwụgwọ. Mgbe a ga-enyocha nyocha nke ọnụ ọgụgụ ogologo oge, na-egosi ndị dị mkpa nke ọbara RtEology mgbe nile. Ọ bụrụ na ịnwere mgbaàmà gastrinestinal, ị nwere ike were ya mgbe nri.

Mmekọrịta ọgwụ ọjọọ

Ngwaahịa a nwere mmetụta Siding na-arụ ọrụ na-eji ọgwụ ndị ọzọ na-eme mgbanwe ọbara, dị ka sodim Alginer na-agbadata, acetate, nke nwere ike ime ka arụmọrụ dịkwuo mma.

Atụmatụ mmepe

Akwụkwọ ginkgo nwere obere ego proanthocyanidins na urushiocle acid, nke ka na-egbu mmadụ. Mgbe akwụkwọ ginkgo dị ka akụrụngwa iji dozie ọgwụgwọ, a chọrọ ọgwụgwọ pụrụ iche iji belata ọdịnaya nke Proanterhocyanidins na urushiolius acid. Agbanyeghị, n'ime usoro a na-eji ugbu a, enweghị oke mma ma ọ bụ na-adịghị ala ala ma ọ nweghị mmetụta na-emetụta Teratogenic. Mpaghara nke Ahụike na-anakwere dị ka ihe mgbakwunye nri ọhụrụ na 1992. N'afọ ndị na-adịbeghị anya, nyocha na mmepe nke Ginkgo biliba nwere atụmanya sara mbara.