Kedu ihe bụ Wheat Germ Extract Spermidine?

Sayensị N'azụ Spermidine

Spermidine bụ polyamine na-eme n'okike nke na-arụ ọrụ dị mkpa na usoro cellular. Polyamines, dị ka spermidine, dị oké mkpa maka uto, mmụgharị na nhazi nke mkpụrụ ndụ. Ogige ndị a na-etinye aka na nhazi nke autophagy, usoro nke anụ ahụ na-emegharị ma na-ehichapụ mkpụrụ ndụ mebiri emebi. Usoro "idebe ụlọ" a dị n'ime bụ ihe dị mkpa maka ahụ ike ma na-ejikọta ya na mbelata nke afọ.

Mmetụta mgbochi ịka nká:A na-ejikọta Spermidine na mmetụta mgbochi ịka nká, ebe a na-achọpụta na ọ na-ebelata ọkwa ya na ịka nká ma na-ejikọta ya na ndụ dị mkpirikpi na ọtụtụ nsogbu, gụnyere nkwụsị nke mgbochi, ọnọdụ mkpali, ọrịa obi ma ọ bụ ụjọ usoro ụjọ, na tumorigenesis.
Ọrụ mgbochi:Spermidine na-arụ ọrụ dị oke mkpa n'ime ọrụ cell na-alụso ọrịa ọgụ, gụnyere ọdịiche na mmezi nke mkpụrụ ndụ T, sel B, na sel egbu egbu (NK). Ọ na-enyekwa aka na polarization nke macrophages n'ebe phenotype na-egbochi mkpali, si otú a na-enyere aka belata mbufụt.
Mmekọrịta na Gut Microbiota:Ihe akaebe na-egosi na eriri afọ microbiota nwere ike ịmepụta spermidine sitere na polyamines ndị ọzọ ma ọ bụ ihe mmalite ha. Mmekọrịta a dị n'etiti nje bacteria na onye ọbịa nwere ike imetụta ọkwa spermidine nke onye ọbịa na ahụike zuru oke.
Nchekwa obi obi:Spermidine egosila mmetụta cardioprotective, nwere ike inye aka na mgbochi nke ọrịa obi.
Neuroprotection: O gosipụtakwala mmetụta neuroprotective, nke nwere ike ịba uru n'ịlụso ọrịa neurodegenerative ọgụ.
Mgbochi Ọrịa Cancer:Site n'ịkwalite immunosurveillance anticancer, spermidine nwere ike inye aka na mgbochi ọrịa kansa.
Iwu Metabolic: Spermidine na-etinye aka na usoro metabolic nke polyamines, nke gụnyere mmekọrịta dị n'etiti onye ọbịa na microbiota ya.
Ọnwụnwa ụlọọgwụ na nchekwa:Ebe ọ bụ na spermidine na-adị na nri mmadụ, a na-ahụta na ọ ga-ekwe omume ịnwale ule ụlọ ọgwụ iji mee ka ọ dị elu. Emekwara nyocha iji nyochaa nchekwa spermidine, mmetụta ahụike, nnabata, metabolism, na bioprocessing.
N'ikpeazụ, spermidine bụ molekul nwere ọtụtụ ihe nwere ike ịpụta maka ahụike mmadụ, gụnyere mgbochi ịka nká, ọrụ nchebe, na nchebe megide ọrịa dị iche iche. Usoro ọrụ ya na-agụnye mmekọrịta ya na microbiota gut, sel ndị na-alụso ọrịa ọgụ, na ụzọ metabolic. Nnyocha ndị ọzọ na nyocha ụlọ ọgwụ nwere ike ịchọpụta ikike ya dị ka onye na-ahụ maka ọgwụgwọ.

Profaịlụ nri nke Germ ọka wheat

Mkpụrụ ọka wit, akụkụ ọmụmụ nke ọka wit, bara ọgaranya nke ukwuu. Ọ nwere nnukwu vitamin E, magnesium, zinc, na fiber. Otú ọ dị, ihe na-eme ka germ ọka wit bụrụ ihe pụrụ iche bụ ihe dị n'ime spermidine. Ọ bụ ezie na obere spermidine dị n'ụdị nri dị iche iche, germ ọka wheat na-enye ụdị gbadoro anya, dị mfe ịnweta.

Protein:Mkpụrụ ọka wheat bụ ezigbo isi iyi nke protein, nwere amino acid asatọ niile dị mkpa, na-eme ka ọ bụrụ isi iyi protein zuru oke.
Fiber:Ọ nwere ma eriri soluble na nke na-adịghị soluble, nke na-enyere aka mgbari nri ma na-enye aka ịhazi ọkwa shuga dị n'ọbara.
Vitamin E:Mkpụrụ ọka wit bụ otu n'ime ihe ndị kasị baa ọgaranya vitamin E, kpọmkwem ụdị tocopherol, nke bụ ike antioxidant.
Vitamin B:Ọ bụ isi iyi nke vitamin B, gụnyere thiamin (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), na folate (B9). Vitamin ndị a na-arụ ọrụ dị mkpa n'ịmepụta ume na nhazi mkpụrụ ndụ ọbara uhie.
Vitamin B12:Ọ bụ ezie na a naghị ahụ ya na nri osisi, germ wheat bụ otu n'ime ihe ọkụkụ ole na ole nke vitamin B12, nke dị mkpa maka ọrụ akwara na mmepụta DNA na RNA.
Acid abụba:Mkpụrụ ọka wit nwere ezigbo nguzozi nke abụba monounsaturated na polyunsaturated, gụnyere omega-3 na omega-6 fatty acids, ndị dị mkpa maka ahụike obi.
mineral:Ọ bụ isi iyi nke mineral dị iche iche dị ka magnesium, phosphorus, potassium, zinc, iron, na selenium, nke dị mkpa maka ọtụtụ ọrụ ahụ.
Phytosterols:Mkpụrụ ọka wit nwere phytosterols, nke bụ ogige osisi na-enyere aka belata ọkwa cholesterol.
Antioxidants:E wezụga vitamin E, germ wheat nwekwara ihe ndị ọzọ na-enyere aka chebe mkpụrụ ndụ pụọ na mmebi nke free radicals kpatara.
Carbohydrates:Ọ na-enye carbohydrates dị mgbagwoju anya, nke na-eji nwayọọ nwayọọ gbarie ma na-enye ike na-adịgide adịgide.
Enwere ike iji nje ọka wheat mee ihe n'ụzọ dị iche iche, dị ka mgbakwunye na smoothies, fesa na ọka, ma ọ bụ dị ka ihe na-esi na ngwaahịa esiri esi. N'ihi nnukwu abụba dị n'ime ya, ọ nwere ike ịghọ ihe na-adịghị mma ma ọ bụrụ na echekwaghị ya nke ọma, ya mere ọ dị mkpa idowe ya na friji ma ọ bụ oyi kpọnwụrụ iji nọgide na-adị ọhụrụ na uru nri.

 

Kedu ka Germ na-ewepụta Spermidine si arụ ọrụ

Ozugbo riri ya, spermidine sitere na germ germ wepụ na-etinye obi gị dum ma malite ọrụ ya na usoro cellular. Otu n'ime usoro ya bụ isi bụ nkwalite ọrụ mitochondrial. Mitochondria, nke a na-akọwakarị dị ka "ụlọ ike" nke cell, na-ahụ maka ịmepụta ike. Site n'ịkwado ọrụ mitochondrial, spermidine ọ bụghị nanị na-enyere aka na mmepụta ume kamakwa ọ na-enye aka belata nrụgide oxidative, bụ isi ihe na-eme ka ịka nká. Nke a bụ ka o si arụ ọrụ n'ime ahụ:

Mmalite nke autophagy:Otu n'ime isi usoro nke spermidine na-eche na ọ na-enye aka na ahụike na ogologo ndụ bụ site na mkpali nke autophagy, usoro cellular nke na-agụnye mmebi na ịmegharị ihe ndị na-emepụta ihe na-emebi emebi. A na-ejikọta usoro a na mkpochapụ nke akụkụ ahụ ndị mebiri emebi na nchịkọta protein, nke nwere ike ịgbakọta na afọ ma tinye aka na ọrịa dị iche iche. Site n'ịkwalite autophagy, spermidine nwere ike inye aka ịnọgide na-enwe ahụ ike na ọrụ cell.

Iwu nke nkwupụta mkpụrụ ndụ ihe nketa:E gosipụtara Spermidine na-emetụta ọnọdụ acetylation nke histones na protein ndị ọzọ, nke nwere ike imetụta mkpụrụ ndụ ihe nketa. Ọ nwere ike igbochi histone acetyltransferases (HATs), na-eduga na deacetylation nke histones na nwere ike ịgbanwe transcription nke mkpụrụ ndụ ihe nketa na-etinye aka na autophagy na usoro cellular ndị ọzọ.

Mmetụta epigenetic:Spermidine nwekwara ike imetụta epigenome site n'ịgbanwe acetylation nke histones, nke bụ protein na gburugburu DNA merụrụ ahụ. Nke a nwere ike imetụta ka e si akọwa mkpụrụ ndụ ihe nketa yana, ya mere, ọrụ ekwentị na ahụike.

Ọrụ Mitochondrial:Ejikọtala Spermidine na arụ ọrụ mitochondrial ka mma, nke dị mkpa maka mmepụta ume n'ime sel. Ọ nwere ike kpalite mmepụta nke mitochondria ọhụrụ ma welie mkpochapụ nke ndị mebiri emebi site na usoro a na-akpọ mitophagy, nke bụ ụdị autophagy nke na-elekwasị anya kpọmkwem mitochondria.

Mmetụta mgbochi mkpali:Spermidine egosipụtala ihe ndị na-egbochi mkpali, nke nwere ike ịba uru n'ibelata mbufụt metụtara ịka nká na ọrịa dị iche iche metụtara afọ.

Nchedo megide nrụgide Oxidative:Dị ka polyamine, spermidine nwere ike ime dị ka antioxidant, na-echebe mkpụrụ ndụ site na mmebi nke ụdị oxygen reactive (ROS) kpatara, nke na-emetụta ịka nká na ọtụtụ ọrịa ndị metụtara afọ.

Mmetụta dị na Sensing Nutrient and Cellular Senescence:Spermidine nwekwara ike na-ekere òkè na ụzọ nhụta nri, nke nwere ike imetụta usoro cellular dị ka uto, mmụba, na metabolism. Atụọla ya ka ọ nwee ike ibelata senescence cellular, ọnọdụ nke njide okirikiri mkpụrụ ndụ agaghị agbanwe agbanwe metụtara ịka nká na ọrịa ndị metụtara afọ.

Usoro ọgwụgwọ akwadoro nke Germ Germ Spermidine

Ndị ọkachamara na-atụ aro itinye spermidine n'ime nri kwa ụbọchị na obere ego a na-achịkwa. Usoro a tụrụ aro maka uru kacha mma dịgasị iche, mana ọtụtụ ọmụmụ na-akwado n'etiti 1 ruo 5 milligrams kwa ụbọchị. Ekwesịrị iji nlezianya rie doses dị elu, ọkachasị n'ụdị mgbakwunye, yana ọ dị mma ka gị na onye ọkachamara ahụike kpọtụrụ tupu ịmalite usoro mgbakwunye ọhụrụ ọ bụla.

Mmechi: Ọdịnihu Na-egbukepụ egbukepụ na Germ Extract Spermidine

spermidine na-amịpụta ọka wheat na-enye ndị na-achọ imeziwanye ahụike na ogologo ndụ ha n'ozuzu ohere. Ikike ya iji kwalite mmụgharị cellular, kwalite ọrụ ọgụgụ isi, na ịkwado usoro ịka nká dị mma na-etinye ya dị ka mgbakwunye na-ekwe nkwa. Site na nyocha gara n'ihu, spermidine nwere ike bụrụ isi nkuku nke ahụike mgbochi n'oge adịghị anya.