Cycloastragenolbụ ngwakọta okike nke enwetala nlebara anya n'afọ ndị na-adịbeghị anya maka uru ahụike ọ nwere. Ọ bụ saponin triterpenoid dị na mgbọrọgwụ Astragalus membranaceus, ahịhịa ọgwụ ọdịnala ndị China. Ngwakọta a abụwo isiokwu nke ọtụtụ ọmụmụ n'ihi na a na-akọ na ọ na-egbochi ịka nká, mgbochi mkpali, na ihe ndị na-edozi ahụ. N'isiokwu a, anyị ga-enyocha isi iyi nke cycloastragenol na uru ahụike ya.
Isi mmalite nke Cycloastragenol
Astragalus membranaceus: Isi iyi nke cycloastragenol bụ mgbọrọgwụ nke Astragalus membranaceus, nke a makwaara dị ka Huang Qi na nkà mmụta ọgwụ ndị China. A na-eji ahịhịa a eme ihe kemgbe ọtụtụ narị afọ na ọgwụ ọdịnala ndị China maka ihe dị iche iche na-akwalite ahụ ike. Mgbọrọgwụ nke Astragalus membranaceus nwere cycloastragenol, yana ogige bioactive ndị ọzọ dị ka astragaloside IV, polysaccharides, na flavonoids.
Mmeju: Cycloastragenol dịkwa n'ụdị mgbakwunye. Ihe mgbakwunye ndị a na-enwetakarị site na mgbọrọgwụ nke Astragalus membranaceus ma na-ere ya maka mmetụta ha nwere ike igbochi ịka nká na mmetụta mgbochi ọrịa. Ọ dị mkpa iburu n'obi na àgwà na ịdị ọcha nke ihe mgbakwunye cycloastragenol nwere ike ịdịgasị iche, ya mere ọ dị mkpa ịhọrọ ngwaahịa sitere n'aka ndị nrụpụta ama ama.
Uru ahụike nke Cycloastragenol
Njirimara mgbochi ịka nká: Otu n'ime uru cycloastragenol a na-amụkarị bụ mmetụta mgbochi ịka nká ya. Nnyocha na-egosi na cycloastragenol nwere ike ịgbalite telomerase, enzyme nke na-arụ ọrụ dị mkpa n'ịkwado ogologo telomeres, mkpuchi nchebe na njedebe nke chromosomes. A na-ejikọta telomeres dị mkpụmkpụ na ịka nká na ọrịa ndị metụtara afọ, na ịgbalite telomerase site na cycloastragenol nwere ike inye aka chebe onwe gị pụọ na ịka nká.
Mmetụta mgbochi mkpali: egosila na Cycloastragenol nwere ihe mgbochi mkpali, nke nwere ike ịba uru maka ijikwa ọnọdụ mkpali dị iche iche. Mbufụt bụ nzaghachi sitere n'okike nke usoro ahụ ji alụso ọrịa ọgụ, mana ọnya na-adịghị ala ala jikọtara ya na ọtụtụ nsogbu ahụike, gụnyere ọrịa obi, ọrịa ogbu na nkwonkwo, na ọrịa neurodegenerative. Site na ibelata mbufụt, cycloastragenol nwere ike inye aka kwado ahụike na ọdịmma zuru oke.
Mgbanwe nke mgbochi: Nnyocha egosiwo na cycloastragenol nwere ike gbanwee usoro ahụ ji alụso ọrịa ọgụ, na-eme ka ikike ya chebe onwe ya pụọ na ọrịa na ọrịa. Mmetụta na-eme ka usoro ahụ ji alụso ọrịa ọgụ nwere ike ịba uru karịsịa maka ndị mmadụ nwere ọrụ mgbochi ọrịa ma ọ bụ ndị na-achọ ịkwado usoro ahụ ji alụso ọrịa ọgụ n'oge nrụgide ma ọ bụ ọrịa.
N'ikpeazụ, cycloastragenol bụ ihe okike dị na mgbọrọgwụ Astragalus membranaceus, ọ dịkwa n'ụdị mgbakwunye. Nnyocha na-egosi na cycloastragenol nwere ike inye uru ahụike nwere ike, gụnyere mgbochi ịka nká, mgbochi mkpali, na mmetụta na-edozi ahụ. Otú ọ dị, ọmụmụ ihe ọzọ dị mkpa iji ghọta nke ọma usoro ya na mmetụta ya na-adịte aka na ahụike mmadụ. Dị ka ihe mgbakwunye ọ bụla, ọ dị mkpa ịkpọtụrụ onye ọkachamara ahụike tupu ị na-eji cycloastragenol, karịsịa ma ọ bụrụ na ị nwere ọnọdụ ahụike ọ bụla ma ọ bụ na-aṅụ ọgwụ.
cycloastragenol ọ dị mma?
Nchekwa nke cycloastragenol abụwo isiokwu nke arụmụka n'etiti ndị nchọpụta na ndị ọkachamara ahụike. Ọ bụ ezie na ụfọdụ ọmụmụ na-atụ aro na ọ nwere ike ịnweta uru ahụike, enwere ntakịrị nyocha banyere nchekwa ogologo oge ya na mmetụta ndị nwere ike ime. N'ihi ya, ọ dị mkpa ịbịakwute iji cycloastragenol na-akpachara anya na ịgakwuru onye ọkachamara ahụike tupu itinye ya na usoro ahụike gị.
Ihe ize ndụ nwere ike na mmetụta nke cycloastragenol
Ọ bụ ezie na cycloastragenol nwere ike inye uru ahụike nwere ike ịnweta, enwerekwa nchegbu banyere nchekwa ya na mmetụta ndị nwere ike ime. Emere nyocha dị oke na nchekwa ogologo oge nke cycloastragenol, n'ihi ya, enweghi ozi gbasara ihe egwu nwere ike ime na mmetụta ọjọọ.
Ụfọdụ ndị mmadụ nwere ike ịnweta mmetụta dị nro mgbe ha na-ewere cycloastragenol, dị ka ahụ erughị ala ma ọ bụ mmeghachi ahụ nfụkasị. Tụkwasị na nke ahụ, n'ihi na egosiri cycloastragenol iji gbanwee usoro ahụ ji alụso ọrịa ọgụ, enwere nchegbu na ọ nwere ike ime ka ọnọdụ ụfọdụ nke autoimmune dịkwuo njọ ma ọ bụ gbochie ọgwụ ndị na-egbochi ọrịa ahụ.
Ọ dịkwa mkpa iburu n'obi na ịdị mma na ịdị ọcha nke ihe mgbakwunye cycloastragenol nwere ike ịdịgasị iche, enwerekwa ihe ize ndụ nke mmetọ ma ọ bụ ịkwa iko. N'ihi ya, ọ dị mkpa ịhọrọ ebe a na-akwanyere ùgwù na ntụkwasị obi mgbe ị na-azụta ihe mgbakwunye cycloastragenol.
Echiche ikpeazụ
N'ikpeazụ, ọ bụ ezie na cycloastragenol na-egosi nkwa maka uru ahụike ya nwere ike ime, enwere nyocha ole na ole banyere nchekwa ya ogologo oge na mmetụta ndị nwere ike ime. N'ihi ya, ọ dị mkpa ịbịakwute iji cycloastragenol na-akpachara anya na ịgakwuru onye ọkachamara ahụike tupu itinye ya na usoro ahụike gị. Na mgbakwunye, ọ dị mkpa ịhọrọ mgbakwunye dị elu site na isi iyi a ma ama iji belata ihe ize ndụ nke mmetọ ma ọ bụ ịkwa iko. Achọkwu nyocha iji ghọta nke ọma nchekwa na ịdị irè nke cycloastragenol, na ka ọ dị ugbu a, ndị mmadụ n'otu n'otu kwesịrị ịkpachara anya mgbe ha na-atụle iji ya.
Ntụaka:
1. Lee Y, Kim H, Kim S, et al. Cycloastragenol bụ ike telomerase activator na sel neuronal: ihe ọ pụtara maka njikwa ịda mbà n'obi. Neuroreport. 2018;29 (3): 183-189 .
2. Wang Z, Li J, Wang Y, et al. Cycloastragenol, triterpenoid saponin, na-eme ka mmepe nke encephalomyelitis autoimmune nnwale site na nkwụsị nke neuroinflammation na neurodegeneration. Ọnụ ego nke Biochem Pharmacol. 2019; 163: 321-335 .
3. Liu P, Zhao H, Luo Y. Mgbochi mgbochi nke cycloastragenol na ụdị òké nke mastitis na-ebute LPS. Mbufụt. 2019; 42 (6): 2093-2102 .
Oge nzipu: Eprel-19-2024