Kedu uru ginsenosides dị?

Ọrụ ọgụgụ isi

Otu n'ime uru ndị a kacha mara amara nke ginsenosides bụ ikike ha nwere imeziwanye ọrụ ọgụgụ isi. Ọtụtụ ọmụmụ egosila na ginsenosides nwere ike ịkwalite ebe nchekwa, mmụta, na arụmọrụ zuru oke. A na-eche na mmetụta ndị a na-edozi site na usoro dị iche iche, gụnyere mgbanwe nke neurotransmitters, dị ka acetylcholine na dopamine, na nkwalite nke neurogenesis, usoro nke ịmepụta neurons ọhụrụ na ụbụrụ.

N'ime nnyocha e bipụtara na Journal of Ethnopharmacology, ndị nchọpụta chọpụtara na ginsenosides nwere ike imeziwanye mmụta mmụta na ebe nchekwa na oke site n'ịkwalite nkwupụta nke ụbụrụ neurotrophic factor (BDNF), protein nke na-akwado ndụ na uto nke neurons. Na mgbakwunye, ginsenosides egosipụtara iji chebe onwe ya pụọ ​​​​na mbelata ọgụgụ isi metụtara afọ na ọrịa neurodegenerative, dị ka ọrịa Alzheimer na ọrịa Parkinson, site na ibelata nrụgide oxidative na mbufụt na ụbụrụ.

Mgbanwe sistemu mgbochi

A chọpụtakwara Ginsenosides na-emezi usoro ahụ ji alụso ọrịa ọgụ, na-eme ka ikike ya chebe onwe ya pụọ ​​​​na ọrịa na ọrịa. E gosiputara ogige ndị a na-akpali mmepụta na ọrụ nke mkpụrụ ndụ na-alụso ọrịa ọgụ dị iche iche, dị ka sel ndị na-egbu egbu, macrophages, na T lymphocytes, bụ ndị na-ekere òkè dị mkpa n'ichebe ahụ pụọ n'ọrịa nje na mkpụrụ ndụ kansa.

Otu nnyocha e bipụtara na akwụkwọ akụkọ International Immunopharmacology gosipụtara na ginsenosides nwere ike ịkwalite nzaghachi mgbochi na ụmụ oke site n'ịba ụba mmepụta nke cytokines, nke na-egosi ụmụ irighiri ihe na-achịkwa ọrụ sel mgbochi. Ọzọkwa, ginsenosides egosiwo na ha nwere ihe mgbochi nje na nje bacteria, na-eme ka ha bụrụ ọgwụgwọ anụ ahụ na-ekwe nkwa maka ịkwado ahụike ahụike na igbochi ọrịa.

Njirimara mgbochi mkpali

Mbufụt bụ mmeghachi omume ebumpụta ụwa nke usoro ahụ ji alụso ọrịa ọgụ na mmerụ ahụ na ọrịa, mana mbufụt na-adịghị ala ala nwere ike inye aka na mmepe nke ọrịa dị iche iche, gụnyere ọrịa obi, ọrịa shuga, na ọrịa kansa. Achọpụtara ginsenosides nwere ihe ndị na-egbochi mkpali, nke nwere ike inye aka belata mmetụta ọjọọ nke mbufụt na-adịghị ala ala na ahụ.

Otu nnyocha e bipụtara na Journal of Ginseng Research gosipụtara na ginsenosides nwere ike igbochi mmepụta nke cytokines pro-inflammatory ma gbochie ịmalite ụzọ mgbaàmà na-egbuke egbuke na sel ndị na-adịghị. Tụkwasị na nke ahụ, ginsenosides egosiwo iji belata okwu nke ndị mgbasa ozi mkpali, dị ka cyclooxygenase-2 (COX-2) na inducible nitric oxide synthase (iNOS), bụ ndị na-etinye aka na nzaghachi mkpali.

Ọrụ mgbochi ọrịa kansa

Akụkụ ọzọ nke mmasị na nyocha ginsenoside bụ ọrụ anticancer ha nwere ike ime. Ọtụtụ nchọpụta egosiwo na ginsenosides nwere ike ịkpata mmetụta mgbochi ọrịa cancer site n'igbochi uto na ịba ụba nke mkpụrụ ndụ cancer, na-ebute apoptosis (ọnwụ cell emebere), na igbochi angiogenesis tumor (nhazi nke arịa ọbara ọhụrụ iji kwado uto tumor).

Nnyocha e bipụtara na International Journal of Molecular Sciences mere ka ọ pụta ìhè ikike anticancer nke ginsenosides, karịsịa na ara, ngụgụ, imeju, na ọrịa cancer colorectal. Ntụleghachi ahụ tụlere usoro dị iche iche nke ginsenosides na-egosipụta mmetụta mgbochi ọrịa cancer ha, gụnyere mgbanwe nke ụzọ mgbaàmà cell, nhazi nke ọganihu cell cell, na nkwalite nke nzaghachi mgbochi megide mkpụrụ ndụ cancer.

Mmechi

N'ikpeazụ, ginsenosides bụ ogige bioactive dị na Panax ginseng nke na-enye ọtụtụ uru ahụike. Ndị a na-agụnye nkwalite n'ịrụ ọrụ ọgụgụ isi, mgbanwe nke usoro ahụ ji alụso ọrịa ọgụ, ihe ndị na-egbochi mkpali, na ọrụ nwere ike igbochi ọrịa kansa. Ọ bụ ezie na achọrọ nyocha ọzọ iji ghọta nke ọma usoro nke ime ihe na ikike ọgwụgwọ nke ginsenosides, ihe àmà ndị dị ugbu a na-egosi na ogige ndị a na-ekwe nkwa dị ka ọgwụgwọ anụ ahụ maka ịkwalite ahụike na ọdịmma zuru oke.

Ntụaka
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 na-egbochi ọrụ nke mkpụrụ ndụ dendritic na mmụba T cell na vitro na in vivo. Immunopharmacology mba ụwa, 17 (3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology nke ginsenosides: nyocha akwụkwọ. Ọgwụ ndị China, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & ojiji nke ginseng na nkà mmụta ọgwụ na-emesi ike na neurodegenerative ọrịa. Akwụkwọ akụkọ sayensị sayensị, 100 (3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, atụmatụ neuroprotective nwere ike. Ngwọta nkwado na ọzọ dabere na akaebe, 2012.
Yun, TK (2001). Okwu mmeghe nke Panax ginseng CA Meyer. Akwụkwọ akụkọ sayensị sayensị Korea, 16 (Suppl), S3.